Polymers duke it out with nucleic acids

Computing with Nucleic Acids

Exactly one decade has passed since Adleman’s seminal demonstration that biochemical operations can be performed on DNA in order to solve certain combinatorial problems [1]. So, the time seems ripe to critically analyze where the field stands, what has been accomplished, what needs to be accomplished, and perhaps most importantly, what are the realistic expectations in this field. A rational as...

Nucleic Acids

The first isolation of what we now refer to as DNA was accomplished by Johann Friedrich Miescher circa 1870. He reported finding a weakly acidic substance of unknown function in the nuclei of human white blood cells, and named this material "nuclein". A few years later, Miescher separated nuclein into protein and nucleic acid components. In the 1920's nucleic acids were found to be major compon...

Nucleic acids.

In: Dyer A, Hudson HG and Williams PA (eds) Ion Exchange Processes: Advances and Applications, p. 39. Cambridge, UK: The Royal Society of Chemistry. Lehto J and Harjula R (1997) Selective separation of radionuclides from nuclear waste solutions with inorganic ion exchangers, React Funct Polym (in press). Navratil JD (1989) Ion exchange technology in spent fuel reprocessing. Journal of Nuclear S...

[Nucleic acids].

E wish to suggest a structure for the salt of deoxyribose nucleic acid (D.N.A.). This structure has novel features which are of considerable biological interest. A structure for nucleic acid has already been proposed by Pauling and Corey. They kindly made their manuscript available to us in advance of publication. Their model consists of three intertwined chains, with the phosphates near the fi...

Nucleic acids.